MovDisordV3, Main, Exploration, bibRecord, 000068

Skin biopsy and I-123 MIBG scintigraphy findings in idiopathic Parkinson's disease and parkinsonism: a comparative study.

Identifieur interne : 000068 ( Main/Exploration ); précédent : 000067; suivant : 000069

Skin biopsy and I-123 MIBG scintigraphy findings in idiopathic Parkinson's disease and parkinsonism: a comparative study.

Auteurs : Maria Pia Giannoccaro [Italie] ; Vincenzo Donadio [Italie] ; Alex Incensi [Italie] ; Fabio Pizza [Italie] ; Ernesto Cason [Italie] ; Vitantonio Di Stasi [Italie] ; Paolo Martinelli [Italie] ; Cesa Scaglione [Italie] ; Sabina Capellari [Italie] ; Giorgio Treglia [Suisse] ; Rocco Liguori [Italie]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.

RBID : pubmed:25778097

Abstract

(123) I-meta-iodobenzylguanidine ((123) I-MIBG) myocardial scintigraphy is considered reliable in differentiating idiopathic Parkinson's disease (IPD) from other parkinsonisms, but it is biased by pharmacological treatments. Skin biopsy is not influenced by therapy and has disclosed skin denervation in IPD. Our aims were to compare (123) I-MIBG scintigraphy and skin biopsy findings in IPD and parkinsonisms to (1) verify whether myocardial and skin denervations are linked; (2) explore the simultaneous extent of the autonomic dysfunction.

DOI: 10.1002/mds.26189
PubMed: 25778097

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">(123) I-meta-iodobenzylguanidine ((123) I-MIBG) myocardial scintigraphy is considered reliable in differentiating idiopathic Parkinson's disease (IPD) from other parkinsonisms, but it is biased by pharmacological treatments. Skin biopsy is not influenced by therapy and has disclosed skin denervation in IPD. Our aims were to compare (123) I-MIBG scintigraphy and skin biopsy findings in IPD and parkinsonisms to (1) verify whether myocardial and skin denervations are linked; (2) explore the simultaneous extent of the autonomic dysfunction.</div>
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Movement Disorders (revue)

Skin biopsy and I-123 MIBG scintigraphy findings in idiopathic Parkinson's disease and parkinsonism: a comparative study.

Skin biopsy and I-123 MIBG scintigraphy findings in idiopathic Parkinson's disease and parkinsonism: a comparative study.

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Abstract

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	Movement Disorders (revue)
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